Oncogene相关论文
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Identification of chromosomal imbalances in pancreatic carcinoma using comparative genomic hybridiza
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目的综述c-ros原癌基因1(c-ros oncogene 1,ROS1)酪氨酸激酶的结构和功能及其抑制剂的研究进展。方法查阅近年来国内外相关文献47......
测定骨髓转移神经母细胞瘤(NB)N-myc扩增情况及评价其与预后的关系.采用差示PCR法检测17例骨髓转移NB的N-myc拷贝数,并随访1年.结......
40. The in vitro Inhibitory Effects of Acanthopanax Giraldii Harms Var. Hispidus Hoo Plant Polysacch
Araliaceal plant polysaccharides have wide biological effects. The antitumor activities of Acanthopanax Giraldii Harms V......
生长相关性癌基因(growth-regulated oncogene-1,GRO-1)是一种具有多种能的趋化因子.它参与机体的多种生理病理过程,在恶性肿瘤演......
癌基因的激活和抑癌基因的缺失或突变是胃癌发病机制中的重要因素[1].人宫颈癌基因(human cervical cancer oncogene,HCCR)是新近......
在体内和细胞内由癌基因诱导的衰老(oncogene-induced senescence,OIS)是一种重要的癌症抑制机制.原癌基因Ras是人类癌症中最易突......
miRNAs are a class of small, ~22nt, non-coding RNAs that negatively regulate gene expression at the post- transcriptiona......
MicroRNAs (miRNAs) play an important role in carcinogenesis in various solid cancers including breast can-cer. Down-regu......
Reactive oxygen species (ROS) are molecules or ions formed by the incomplete one-electron reduction of oxygen. Ofinteres......
RNA interference of pax2 inhibits growth of transplanted human endometrial cancer cells in nude mice
The development of human endometrial carcinoma(HEC) is a complex pathologic process involves several oncogenes and tumor......
microRNAs是一类新型保守的微小非编码单链RNA,成熟的microRNAs通过与靶基因mRNA碱基形成不完全配对,引起mRNA降解及转录抑制.研究......
MicroRNA (miRNA)为非编码的单链小RNA分子,具有高度保守性、时序性和组织特异性.MicroRNA-22(miR-22)参与了骨骼代谢、心肌细胞成......
肿瘤的发生是与肿瘤相关基因的行为有很大的关系。本文综述了癌基因和抑癌基因的定义,原癌基因的最新发现,抑癌基因的研究进展,以......
Identification of chromosomal imbalances in pancreatic carcinoma using comparative genomic hybridiza
Objective To identify genetic abnormalities in primary pancreatic carcinoma in humans.Methods Comparative genomic hybr......
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Inhibition of human esophageal squamous cell carcinomas by targeted silencing of tumor enhancer gene
Esophageal cancer has been reported as the ninth most common malignancy and ranks as the sixth most frequent cause of de......
N6-methyladenosine (m6A) is an essential RNA modification that regulates key cellular processes, including stem cell ren......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
miR-100既可表现出致癌基因的作用，又可表现出抑癌基因的作用，其不仅在多种肿瘤（宫颈癌、前列腺癌、膀胱癌和肺癌等）的发生、发展中发......
YAP是Hippo信号通路的核效应因子,是此信号通路中高度保守的成分,在细胞增殖和凋亡过程中起重要作用.已发现在多种恶性肿瘤中存在Y......
Correlation of Kif2a and HPK1 expression in breast cancer with the oncogene and drug resistance gene
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Relationship of the ultrasonic elastography parameter of thyroid carcinoma with the cancer cell grow
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Mutational activation of KRAS is a common oncogenic event in lung cancer and other epithelial cancer types.Efforts to de......
Correlation of serum ROBO4 and sB7-H4 contents with the pathological features of tumor in patients w
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
40. The in vitro Inhibitory Effects of Acanthopanax Giraldii Harms Var. Hispidus Hoo Plant Polysacch
Araliaceal plant polysaccharides have wide biological effects. The antitumor activities of Acanthopanax Giraldii Harms V......
高迁移率族蛋白A1(HMGA1)属于高迁移率蛋白家族(HMG),在人体中分布广泛,参与多种生理病理过程.研究发现其在多种肿瘤,包括在白血病......
病毒感染与癌症的关系是生物医学领域中非常重要的研究方向,估计当前全世界至少20%人类肿瘤的发生与病毒感染有密切联系.本文对反......
INTRODUCTION The esophageal carcinoma is a common malignant tumor in Linzhou City (Linxian) of Henan Province in norther......
原癌基因的激活是包括肺癌在内的众多恶性肿瘤的重要特征,而原癌基因发生扩增被认为在原癌基因激活过程中起着重要作用.随着分子遗......
Objective: To investigate the mutual relation of the changesamong multiple genes in human gastric carcinomas (GC). Metho......
Inhibition of human esophageal squamous cell carcinomas by targeted silencing of tumor enhancer gene
Esophageal cancer has been reported as the ninth most common malignancy and ranks as the sixth most frequent cause of de......
The changes of expression and function of MDM2 and P53 by MDM2 specific antisense oligonucleotides were investigated in ......
MDM2 (the product of murine double minute 2 gene) is one of the most important negative regulators of p53, which can bin......
目的检测p53和c-myc蛋白在早期喉癌手术切缘组织中的表达及其与肿瘤局部复发的关系。方法选择2004—2010年间唐山市协和医院185例......
Mouse models of cancer enable researchers to learn about tumor biology in complicated and dynamic physiological systems.......
miR-100既可表现出致癌基因的作用，又可表现出抑癌基因的作用，其不仅在多种肿瘤（宫颈癌、前列腺癌、膀胱癌和肺癌等）的发生、发展中发......
目的 检测Survivin抑制后PC-3细胞微小RNA( miRNAs)表达谱的变化,探讨Survivin与相关miRNAs之间的关系.方法 利用负载Survivin短发......
microRNA(miRNA)是一种大小为18～25个碱基的单链小分子的非编码RNA.miRNA在消化系统肿瘤的发生发展中都发挥着重要的作用.目前已经......
作为胃肠外科的研究重点和热点之一,胃肠间质瘤发生发展的部分重要机制如其确切的起源、为何R0切除后仍高复发等尚不明了.本文拟结......
The full length cDNA coding for P15 INK4b, which is a cyclin-dependent kinase inhibitor, was cloned to plasmid PXJ41-neo......
The influence mechanism of the nano-apatite on the human hepatocellular carcinoma in vitro was investigated. Using the h......
目的探讨肝细胞癌(HCC)患者血清常见的癌基因和抑癌基因水平变化。方法2017年7月~2020年7月我院收治的慢性乙型肝炎患者40例,代偿......
肝细胞癌是严重影响人类健康的疾病,其发生发展机制尚不完全明确,治疗也面临众多的难题。SIRT1是Sirtuin家族中定位于细胞核的基因......
口腔鳞癌的发病机制非常复杂,目前仍未明确。研究发现lncRNA是肿瘤中的一组重要的调节因子,与口腔鳞癌的发生发展密切相关,本文就l......
骨肉瘤是一类起源于间叶组织的好发于长管状骨的原发性恶性骨肿瘤,其组织学特征为梭形肿瘤细胞可产生骨样基质或不成熟骨。患者早......
目的研究不同年龄段乳腺癌患者的临床病理特征。方法选择就诊的乳腺癌患者,根据年龄分为≤40岁组、41～54岁组、≥55岁组,观察TNM分......
综述了结构基因组学的研究进展，在基因组学水平上对癌症的研究现状及其在癌症研究中的应用。......
